Student's Corner

Pathophysiology and treatment of significant bleeding oesophageal varices

Jennifer Margaret Lee
Department of Nursing, Charles Sturt University, Bathurst NSW

PP: 221 - 226

Abstract

Acute oesophageal variceal haemorrhage is a major cause of death associated with cirrhotic liver disease. Whilst surgical procedures can decrease the risk of recurrent bleeds, pharmacological aids are often used to treat the cause of the varices: portal hypertension. Insertion of a Sengstaken Blakemore tube or Minnesota tube can temporarily halt the haemorrhage by exerting pressure on the varices.

This pressure decreases the blood supply to the oesophagus, thereby decreasing the amount of blood lost through a ruptured vessel. The use of these tubes is based on individual hospital policy. Other techniques such as band ligation, are also being introduced for the management of oesophageal varices to decrease haemorrhaging. Once the bleeding has been controlled surgical procedures such as sclerotherapy can attempt to permanently stop the rupture. However, these procedures do not treat the cause of the varices. Adjunctive medications, transplants and shunts attempt to permanently decrease the portal hypertension in order to decrease the risk of recurrent haemorrhage.

Keywords

oesophageal varices; portal hypertension; rupture; tamponade


View references

References

Brown, D., & Edwards, H. (2009). Lewis's medical surgical nursing (2nd ed.). Sydney, NSW: Elsevier.

Bryant, B., & Knights, K. (2009). Pharmacology for health professionals (2nd ed.). Sydney, NSW: Elsevier.

Bullock, S., Manias, E., & Galbraith, A. (2007). Fundamentals of pharmacology (5th ed.). Sydney, NSW: Pearson Education.

Chang, Y. W. (2006). Indications of treatment for esophageal varices: Who and when? Digestive Endoscopy, 18, 10-15.

Christensen, T. (2004). The treatment of oesophageal varices using a Sengstaken-Blakemore tube: Considerations for nursing practice. Nursing in Critical Care, 9(2), 58-63.

Corwin, E. J. (2008). Handbook of pathophysiology. Philadelphia, PA: Lippincott Williams & Wilkins.

Cowles, R. A. (2009, January 30). Transjugular intrahepatic portosystemic shunt (TIPS). Medline Plus. Retrieved September 3, 2010, from http://www.nlm.nih.gov/medlineplus/ency/article/007210.htm

Devrajani, B. R., Soomro, A. A., Attra, K. M., & Ali Qureshi, G. (2010). Variceal bleeding and its dependence on portal vein size in the liver cirrhotic patients. Advances in Medical and Dental Sciences, 3(3), 60-64.

Garcia-Tsao, G., & Bosch, J. (2010). Management of varices and variceal hemorrhage in cirrhosis. The New England Journal of Medicine, 362(9), 823-832.

Greenwald, B. (2004). The Minnesota tube, its use and care in bleeding esophageal and gastric varices. Gastroenterology Nursing, 27(5), 212-217.

Hay, D. W. (2006). The little black book of gastroenterology. Sudbury, MA: Jones and Bartlett.

Kawaoka, T., Takahashi, S., Aikata, H., Azakami, T., Saneto, H., Takaki, S., et al. (2008). Benificial effects of living-donor transplantation on esophageal varices. Journal of Gastroenterology, 43, 982-989.

Lo, G.-H., Chen, W.-C., Chan, H.-H., Tsai, W.-L., Hsu, P.-I., Lin, C.-K., et al. (2009). A randomized, controlled trial of banding ligation plus drug therapy versus drug therapy alone in the prevention of esophageal variceal rebleeding. Journal of Gastroenerology and Hepatology, 24, 982-987.

Lubel, J. S., & Angus, P. W. (2005). Modern management of portal hypertension. Internal Medicine Journal, 35, 45-49.

Petrasch, F., Grothaus, J., Mossner, J., Schiefke, I., & Hoffmeister, A. (2010, January 15). BMC gastroenterology. BioMedical Central. Retrieved August 5, 2010, from http://www.biomedcentral.com/1471-230X/10/5

Porth, C. M. (2007). Essentials of pathophysiology. Concepts of altered health states. Philadelphia, PA: Lippincott Williams & Wilkins.

Remesz, O. (2010). Sengstaken-Blakemore tube with four lumes [image]. Retrieved June 11, 2011, from http://en.wikipedia.org/wiki/Sengstaken-Blakemore_tube

Rochling, F. A., & Zetterman, R. K. (2009). Management of ascites. Drugs, 69(13), 1739-1760.

Sarangapani, A., Shanmugam, C., Kalyanasundaram, M., Rangachari, B., Thangavelu, P., & Subbarayan, J. K. (2010). Non-invasive prediction of large esophageal varices in chronic liver disease patients. The Saudi Journal of Gastroenterology, 16(1), 38-42.

Sarwar, S., Azeem, M., Ayub, M., Latif, H., Butt, N. F., Shabbir, B., et al. (2010). Optimum therapy for secondary prophylaxis of variceal bleeding patient: Endoscopic, pharmacological or combination, a randomized study. Annals of King Edward Medical University, 16(1), 69-72.

Seet, E., Beevee, S., Cheng, A., & Lim, E. (2008). The Sengstaken-Blakemore tube: Uses and abuses. Singapore Medical Journal, 49(8), 195-197.

Springings, D. C., & Chambers, J. B. (2008). Acute medicine, a practical guide to the management of medical emergencies. Melbourne, VIC: Blackwell.

The Royal College of Radiologists. (2009, August 3). TIPSS (Transjugular Intrahepatic PortoSystemic Shunt). Retrieved September 3, 2010, from http://www.suht.nhs.uk/OurServices/Operationsandtests/Radiology/PatientInformation/TIPSS.aspx

Trotter, J. F. (2006). Advances in endoscopy. Gastroenterology and Hepatology, 2(7), 494-495.

Villanueva, C., & Balanz, J. (2008). Variceal bleeding, pharmacological treatment and prophylactic strategies. Drugs, 68(16), 2303-2324.

Wang, J., & Cosby, H. (2010). Liver transplant workup [image]. Johns Hopkins Medicine, Gastroenterology & Hepatology. Retrieved September 3, 2010, from www.hopkins-gi.org



RSS Facebook Twitter

Sign Me Up for latest release updates

*  Email Address:
    First Name:
    Last Name:
*  I am interested in::





 

Web Feed

Latest Articles

Special Issues

Advances in Contemporary Health Care for Vulnerable Populations
Volume 42/1
Summary | Contents


Advances in Contemporary Community & Family Health Care (3rd edn)
Volume 41/1
Summary | Contents


Advances in Contemporary Complex Health Care: Nursing Interventions
Volume 40/2
Summary | Contents


Advances in Contemporary Community and Family Health Care (2nd edn)
Volume 40/1
Summary | Contents


Advances in Contemporary Nurse Education (2nd edn)
Volume 38/1-2
Summary | Contents


Advances in Contemporary Indigenous Health Care (2nd edn)
Volume 37/1
Summary | Contents


Advances in Contemporary Nursing: Workforce and Workplaces
Volume 36/1-2
Summary | Contents


Advances in Contemporary Modeling of Clinical Nursing Care
Volume 35/2
Contents


Advances in Contemporary Mental Health Nursing (2nd edn)
Volume 34/2
Summary | Contents


Advances in Contemporary Nursing and Gender
Volume 33/2
Summary | Contents


Advances in Contemporary Nurse Education
Volume 32/1-2
Summary | Contents


Advances in Contemporary Nursing: History of Nursing and Midwifery in Australasia
Volume 30/2
Summary | Contents


crossref.org - The citation linking backbone



Website by Arrowsmith Websites. Website Design Sunshine Coast, Australia.